BDBM104231 US8575145, 108

SMILES Fc1cc(OCC2(F)CNC2)c2nc(ccc2c1)-c1nnc2ccccn12

InChI Key InChIKey=OIHRVTLGUCLTFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 104231   

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104231(US8575145, 108)
Affinity DataIC50: 7.30nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104231(US8575145, 108)
Affinity DataIC50: 489nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent