BDBM10622 (-)-Phenserine::(3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-phenylcarbamate::CHEMBL54727
SMILES CN1CC[C@]2(C)C1N(C)c1ccc(OC(=O)Nc3ccccc3)cc21
InChI Key InChIKey=PBHFNBQPZCRWQP-IJHRGXPZSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 10622
Affinity DataIC50: 22nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+3nMAssay Description:Ability to inhibit butyrylcholinesterase (BChE), freshly prepared from human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition acetylcholinesterase (AChE) enzyme.More data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Meiji Pharmaceutical University
Curated by ChEMBL
Meiji Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of BuChE in Wistar rat plasma using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 28.3nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Ability to inhibit acetylcholinesterase (AChE), freshly prepared from human erythrocytesMore data for this Ligand-Target Pair