BDBM10691 (-)-N1-benzylnorphysostigmine::(3aS)-8-benzyl-1,3a-dimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate::CHEMBL80221

SMILES CNC(=O)Oc1ccc2N(Cc3ccccc3)C3N(C)CC[C@@]3(C)c2c1

InChI Key InChIKey=MFSFKJAYNZMHEN-QWAKEFERSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10691   

TargetAcetylcholinesterase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM10691((-)-N1-benzylnorphysostigmine | (3aS)-8-benzyl-1,3...)
Affinity DataIC50:  161nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10691((-)-N1-benzylnorphysostigmine | (3aS)-8-benzyl-1,3...)
Affinity DataIC50:  21.8nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM10691((-)-N1-benzylnorphysostigmine | (3aS)-8-benzyl-1,3...)
Affinity DataIC50:  161nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10691((-)-N1-benzylnorphysostigmine | (3aS)-8-benzyl-1,3...)
Affinity DataIC50:  21.8nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed