BDBM11294 5-[(4-chlorobenzene)sulfonyl]pyrimidine-2,4-diamine::Compound 1 analog 5::acs.jmedchem.1c00409_ST.436::cmdc.202100576, 7e

SMILES Nc1ncc(c(N)n1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=RPPFHWBHHCJZJS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11294   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11294(5-[(4-chlorobenzene)sulfonyl]pyrimidine-2,4-diamin...)
Affinity DataIC50:  6.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11294(5-[(4-chlorobenzene)sulfonyl]pyrimidine-2,4-diamin...)
Affinity DataIC50:  6.00E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11294(5-[(4-chlorobenzene)sulfonyl]pyrimidine-2,4-diamin...)
Affinity DataIC50:  6.00E+3nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed