BDBM1173 N-(3-{cyclopropyl[4-hydroxy-2-oxo-6-(2-phenylethyl)-2H-pyran-3-yl]methyl}phenyl)-1-methyl-1H-imidazole-4-sulfonamide::N-[3-[Cyclopropyl(4-hydroxy-2-oxo-6-(2-phenylethyl)-2H-pyran-3-yl)methyl]phenyl]-1-methyl-1H-imidazole-4-sulfonamide::Sulfonamide-Containing 4-Hydroxy-2-pyrone deriv. XIII

SMILES Cn1cnc(c1)S(=O)(=O)Nc1cccc(c1)C(C1CC1)c1c(O)cc(CCc2ccccc2)oc1=O

InChI Key InChIKey=OKNWBOKCZOFVKS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1173   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1173(N-(3-{cyclopropyl[4-hydroxy-2-oxo-6-(2-phenylethyl...)
Affinity DataKi:  0.970nM ΔG°:  -12.2kcal/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
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