BDBM11888 N-Hydroxy-2-[(4-phenoxyphenyl)sulfonyl]acetamide::N-hydroxy-2-[(4-phenoxybenzene)sulfonyl]acetamide::alpha-sulfone 13

SMILES ONC(=O)CS(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=VFZUVETVSPJFEB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11888   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM11888(N-Hydroxy-2-[(4-phenoxyphenyl)sulfonyl]acetamide |...)
Affinity DataKi:  2.60nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

LigandPNGBDBM11888(N-Hydroxy-2-[(4-phenoxyphenyl)sulfonyl]acetamide |...)
Affinity DataKi:  5.10nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM11888(N-Hydroxy-2-[(4-phenoxyphenyl)sulfonyl]acetamide |...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed