BDBM119254 US8673906, 3.14::US8673906, 8::US9718800, 8.0

SMILES CC(Nc1cc(F)cc(Cl)c1)c1cc(cc2c1oc(cc2=O)N1CCOCC1)C(=O)N(C)C

InChI Key InChIKey=AVJHOQVVSKUYKV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 119254   

LigandPNGBDBM119254(US8673906, 3.14 | US8673906, 8 | US9718800, 8.0)
Affinity DataIC50:  4nMAssay Description:The inhibition of PI3Kβ, PI3Kα, PI3Kγ and PI3Kδ was evaluated in a Kinase Glo based enzyme activity assay using human recombinant...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM119254(US8673906, 3.14 | US8673906, 8 | US9718800, 8.0)
Affinity DataIC50:  3nMT: 2°CAssay Description:Compounds in 100% DMSO were added to assay plates by acoustic dispensing. PI3Kβ was added in a Tris buffer (50 mM Tris pH7.4, 0.05% CHAPS, 2.1 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM119254(US8673906, 3.14 | US8673906, 8 | US9718800, 8.0)
Affinity DataIC50:  4nMT: 2°CAssay Description:Compounds in 100% DMSO were added to assay plates by acoustic dispensing. PI3Kβ was added in a Tris buffer (50 mM Tris pH7.4, 0.05% CHAPS, 2.1 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM119254(US8673906, 3.14 | US8673906, 8 | US9718800, 8.0)
Affinity DataIC50:  3nMAssay Description:The inhibition of PI3Kβ, PI3Kα, PI3Kγ and PI3Kδ was evaluated in a Kinase Glo based enzyme activity assay using human recombinant...More data for this Ligand-Target Pair
In DepthDetails US Patent