BDBM12 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoic acid::Biotin::cid_171548::cid_253

SMILES: C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2

InChI Key: InChIKey=YBJHBAHKTGYVGT-UHFFFAOYSA-N

Data: 2 IC50  1 Kd  21 ITC

PDB links: 132 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Human)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	529	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.73	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Streptavidin (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 21 hits for monomerid = 12

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
Streptavidin (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-29.4	n/a	7	37
TBA					Details of this binding reaction
Streptavidin (Y43F) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-28.2	n/a	7	37
TBA					Details of this binding reaction
Streptavadin(Y43A) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-21.6	n/a	7	37
TBA					Details of this binding reaction
Streptavadin(S27A) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-24.5	n/a	7	37
TBA					Details of this binding reaction
Streptavadin(N23E) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-25.7	n/a	7	37
TBA					Details of this binding reaction
Streptavadin(N23A) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-21.5	n/a	7	37
TBA					Details of this binding reaction
Streptavidin (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-24.9	n/a	7	25
TBA					Details of this binding reaction
Streptavidin (Y43F) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-27.5	n/a	7	25
TBA					Details of this binding reaction
Streptavadin(Y43A) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-16.0	n/a	7	25
TBA					Details of this binding reaction
Streptavadin(S27A) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-23.3	n/a	7	25
TBA					Details of this binding reaction
Streptavadin(N23E) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-24.0	n/a	7	25
TBA					Details of this binding reaction
Streptavadin(N23A) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-18.0	n/a	7	25
TBA					Details of this binding reaction
BirA Bifunctional Protein (Escherichia coli (strain K12))	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			-9.82	9.39	-19.4	7.37	7.5	20
TBA					Details of this binding reaction
BirA Bifunctional Protein Mutant (W223A) (Escherichia coli)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			-9.78	9.78	-19.6	7.33	7.5	20
TBA					Details of this binding reaction
BirA Bifunctional Protein Mutant (V214A) (Escherichia coli)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			-9.88	9.59	-19.5	7.42	7.5	20
TBA					Details of this binding reaction
BirA Bifunctional Protein Mutant (V219A) (Escherichia coli)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			-9.98	9.28	-19.4	7.42	7.5	20
TBA					Details of this binding reaction
BirA Bifunctional Protein (Escherichia coli (strain K12))	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			-9.87	9.28	-19.2	7.38	7.5	20
TBA					Details of this binding reaction
Streptavidin (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-24.5	n/a	n/a	25
TBA					Details of this binding reaction
Streptavadin(W79F) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-26.0	n/a	n/a	25.3
TBA					Details of this binding reaction
Streptavadin(W108F) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-23.5	n/a	n/a	25.2
TBA					Details of this binding reaction
Streptavadin(W120F) (Streptomyces avidinii)	BDBM12 (cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)	GoogleScholar			n/a	n/a	-19.4	n/a	n/a	25
TBA					Details of this binding reaction