BDBM12127 3-(Indol-2-yl)indazole 17::6-(5-methyl-1H-1,2,3-triazol-1-yl)-3-[5-(piperidin-1-ylmethyl)-1H-indol-2-yl]-1H-indazole

SMILES Cc1cnnn1-c1ccc2c(n[nH]c2c1)-c1cc2cc(CN3CCCCC3)ccc2[nH]1

InChI Key InChIKey=GVOOLHNJOQWXKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12127   

TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM12127(3-(Indol-2-yl)indazole 17 | 6-(5-methyl-1H-1,2,3-t...)
Affinity DataIC50:  420nMAssay Description:The IMAP technology is based on the high affinity binding of phosphate by immobilized metal coordination complexes on nanoparticles. This IMAP bindin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM12127(3-(Indol-2-yl)indazole 17 | 6-(5-methyl-1H-1,2,3-t...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Kinase activity was measured in a homogeneous assay in a 96-well format. Detection was performed by HTRF using an EuK-labelled anti-phospho(S21)-GSK3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed