BDBM12182 (2S)-1-[(2S)-2-amino-4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)butanoyl]pyrrolidine-2-carbonitrile::CHEMBL179289::cyanopyrrolidine derivative 5

SMILES N[C@@H](CC(=O)N1CCc2ccccc2C1)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=XCUPYUKEECXEPG-HOTGVXAUSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 12182   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12182((2S)-1-[(2S)-2-amino-4-oxo-4-(1,2,3,4-tetrahydrois...)
Affinity DataIC50:  19nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12182((2S)-1-[(2S)-2-amino-4-oxo-4-(1,2,3,4-tetrahydrois...)
Affinity DataIC50:  63nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12182((2S)-1-[(2S)-2-amino-4-oxo-4-(1,2,3,4-tetrahydrois...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration against Dipeptidyl-peptidase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12182((2S)-1-[(2S)-2-amino-4-oxo-4-(1,2,3,4-tetrahydrois...)
Affinity DataIC50:  99nMAssay Description:Inhibitory concentration against Dipeptidyl-peptidase IV [DPP-IV]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12182((2S)-1-[(2S)-2-amino-4-oxo-4-(1,2,3,4-tetrahydrois...)
Affinity DataIC50:  3.13E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed