BDBM128498 US8796244, 77

SMILES Cc1cc2ncc(-c3cccc(NC(=O)NCC(F)(F)F)c3)n2cc1C

InChI Key InChIKey=RPXLWISPHFODGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128498   

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM128498(US8796244, 77)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM128498(US8796244, 77)
Affinity DataIC50: 2.70E+3nMpH: 8.0 T: 2°CAssay Description:VEGFR2 (from Upstate), prepared at 2x final concentration, was incubated with test compounds, biotinylated Flt3 substrate (biotin-VASSDNEYFYVDF) (Cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent