BDBM13055 CHEMBL283695::Compound 8::Topiramate Sulfamide Analogue 8::amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl}sulfonamide

SMILES: CC1(C)O[C@@H]2CO[C@@]3(CNS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1

InChI Key: InChIKey=NQRKKQKMTGLNOZ-UHFFFAOYSA-N

Data: 38 KI  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 13055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.50E+4	n/a	n/a	n/a	7.5	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 5B, mitochondrial (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 5B, mitochondrial (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 5B, mitochondrial (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 14 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 14 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 14 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Mouse)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Mouse)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Mouse)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		941	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		941	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		941	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.14E+3	-7.65	n/a	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		3.45E+3	-7.37	n/a	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		6.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 3 (Human)	BDBM13055 (amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair