BDBM13428 (15S)-4-ethyl-15-methyl-5-(sulfamoyloxy)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-trien-14-yl sulfamate::oestrogen deriv. 13

SMILES CCc1cc2C3CC[C@]4(C)C(CCC4C3CCc2cc1OS(N)(=O)=O)OS(N)(=O)=O

InChI Key InChIKey=LDOGEZTUWBORPG-OTTZRNNHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13428   

TargetSteryl-sulfatase(Homo sapiens (Human))
St. Mary'S Hospital

LigandPNGBDBM13428((15S)-4-ethyl-15-methyl-5-(sulfamoyloxy)tetracyclo...)
Affinity DataIC50:  1.90E+3nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
St. Mary'S Hospital

LigandPNGBDBM13428((15S)-4-ethyl-15-methyl-5-(sulfamoyloxy)tetracyclo...)
Affinity DataIC50:  290nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed