BDBM13945 APC-13140::[amino(2-{hydroxy[(3-phenoxyphenyl)methyl]carbamoyl}-1H-1,3-benzodiazol-5-yl)methylidene]azanium

SMILES NC(=[NH2+])c1ccc2nc([nH]c2c1)C(=O)N(O)Cc1cccc(Oc2ccccc2)c1

InChI Key InChIKey=JEEKJSJMJKETGC-UHFFFAOYSA-O

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13945   

TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13945(APC-13140 | [amino(2-{hydroxy[(3-phenoxyphenyl)met...)
Affinity DataKi:  380nM ΔG°:  -8.66kcal/molepH: 7.7 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13945(APC-13140 | [amino(2-{hydroxy[(3-phenoxyphenyl)met...)
Affinity DataKi:  400nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13945(APC-13140 | [amino(2-{hydroxy[(3-phenoxyphenyl)met...)
Affinity DataKi:  3.80E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed