BDBM140227 US8906911, 36

SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1cc(ccc1C(F)(F)F)C#N

InChI Key InChIKey=UQNIMNLVIUOOGI-BHDKNMHBSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140227   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM140227(US8906911, 36)
Affinity DataKi:  1.06E+3nM ΔG°:  -7.57kcal/mole IC50:  305nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In DepthDetails US Patent