BDBM14672 2-hydroxypropane-1,2,3-tricarboxylic acid::CHEMBL1261::Citrate::Citric Acid::Fragment 2::cid_311

SMILES OC(=O)CC(O)(CC(O)=O)C(O)=O

InChI Key InChIKey=KRKNYBCHXYNGOX-UHFFFAOYSA-N

Data  1 KI  6 IC50  2 Kd

PDB links: 1411 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 14672   

TargetBeta-lactamase(Bacillus licheniformis)
Universit£

Curated by ChEMBL
LigandPNGBDBM14672(2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL...)
Affinity DataKi:  4.90E+5nMpH: 5.0Assay Description:Inhibition of Bacillus licheniformis BS3 beta-lactamase at pH 5More data for this Ligand-Target Pair
TargetHepatocyte nuclear factor 4-alpha(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM14672(2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL...)
Affinity DataIC50: >3.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPerilipin-1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM14672(2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL...)
Affinity DataIC50:  3.71E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPerilipin-5(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM14672(2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL...)
Affinity DataIC50:  5.63E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProlyl 4-hydroxylase(Paramecium bursaria Chlorella virus 1)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM14672(2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL...)
Affinity DataIC50:  2.13E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-dehydroquinate dehydratase(Streptomyces coelicolor)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM14672(2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL...)
Affinity DataKd:  7.30E+3nMAssay Description:Binding affinity for Streptomyces coelicolor DHQase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM14672(2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src [145-252](Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM14672(2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL...)
Affinity DataIC50: >4.00E+7nMpH: 7.4 T: 2°CAssay Description:SPA uses 125I as energy donor and scintillant-coated beads as energy acceptor. The labeled ligand is captured by the biotinylated Src-SH2 protein imm...More data for this Ligand-Target Pair
Target3-dehydroquinate dehydratase(Helicobacter pylori)
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM14672(2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL...)
Affinity DataKd:  2.50E+3nMAssay Description:Binding affinity for Helicobacter pylori DHQase 2More data for this Ligand-Target Pair