BDBM14830 (+/-)1-[5-Chloro-2-(3-methyl-oxetan-3-ylmethoxy)-phenyl]-3-(5-cyano-pyrazin-2-yl)-urea::3-{5-chloro-2-[(3-methyloxetan-3-yl)methoxy]phenyl}-1-(5-cyanopyrazin-2-yl)urea::A-641397::urea-based inhibitor 2e

SMILES: CC1(COc2ccc(Cl)cc2NC(=O)Nc2cnc(cn2)C#N)COC1

InChI Key: InChIKey=PCXWBHWJIHAPAY-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Human)	BDBM14830 ((+/-)1-[5-Chloro-2-(3-methyl-oxetan-3-ylmethoxy)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
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