BDBM14948 4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(3-(trifluoromethyl)phenyl)benzamide::4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)-N-[3-(trifluoromethyl)phenyl]benzamide::pyridinyl pyrimidine 15::pyridylpyrimidine ether 4

SMILES: CNc1nccc(n1)-c1cccnc1Oc1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=ZVIWALRWYYSHSU-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 14948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Human)	BDBM14948 (4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	22
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Vascular endothelial growth factor receptor 2 (Human)	BDBM14948 (4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck [245-498] (Human)	BDBM14948 (4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM14948 (4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	22
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM14948 (4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Yes (Human)	BDBM14948 (4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Yes (Human)	BDBM14948 (4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair