BDBM14970 4-Methyl-3-(2-(quinoxalin-2-yl)ethynyl)-N-(3-(trifluoromethyl)phenyl)benzamide::4-methyl-3-[2-(quinoxalin-2-yl)ethynyl]-N-[3-(trifluoromethyl)phenyl]benzamide::heterocyclic akynyl amide 13e

SMILES Cc1ccc(cc1C#Cc1cnc2ccccc2n1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=AIMHAFQTBGSBMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14970   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM14970(4-Methyl-3-(2-(quinoxalin-2-yl)ethynyl)-N-(3-(trif...)
Affinity DataIC50:  85nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck [245-498](Homo sapiens (Human))
Amgen

LigandPNGBDBM14970(4-Methyl-3-(2-(quinoxalin-2-yl)ethynyl)-N-(3-(trif...)
Affinity DataIC50:  4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM14970(4-Methyl-3-(2-(quinoxalin-2-yl)ethynyl)-N-(3-(trif...)
Affinity DataIC50:  4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed