BDBM14998 2-(Methylamino)triazine 61::N-(2-((3-(Dimethylamino)propyl)(methyl)amino)-5-(trifluoromethyl)phenyl)-4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)benzamide::N-(2-{[3-(dimethylamino)propyl](methyl)amino}-5-(trifluoromethyl)phenyl)-4-methyl-3-({3-[4-(methylamino)-1,3,5-triazin-2-yl]pyridin-2-yl}oxy)benzamide

SMILES CNc1ncnc(n1)-c1cccnc1Oc1cc(ccc1C)C(=O)Nc1cc(ccc1N(C)CCCN(C)C)C(F)(F)F

InChI Key InChIKey=TYDADJOKJRXQDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14998   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM14998(2-(Methylamino)triazine 61 | N-(2-((3-(Dimethylami...)
Affinity DataIC50:  4.00E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM14998(2-(Methylamino)triazine 61 | N-(2-((3-(Dimethylami...)
Affinity DataIC50:  59nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed