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BDBM15303 (5R)-5-methyl-6-{4-[(2-methyl-3-oxocyclohex-1-en-1-yl)amino]phenyl}-2,3,4,5-tetrahydropyridazin-3-one::dihydropyridazinone 8b
SMILES: C[C@@H]1CC(=O)NN=C1c1ccc(NC2=C(C)C(=O)CCC2)cc1
InChI Key: InChIKey=FGECETOGIKDEKR-UHFFFAOYSA-N
Data: 2 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112] (Human) | BDBM15303![]() ((5R)-5-methyl-6-{4-[(2-methyl-3-oxocyclohex-1-en-1...) | GoogleScholar | UniChem | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | 7.5 | 22 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [388-1112] (Human) | BDBM15303![]() ((5R)-5-methyl-6-{4-[(2-methyl-3-oxocyclohex-1-en-1...) | GoogleScholar | UniChem | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||