BDBM153657 US8999998, 38
SMILES Cc1cc(NC(=O)c2cnn3cccnc23)n(n1)-c1cc(ccc1C)C#N
InChI Key InChIKey=IFTUJXXKLGWTIY-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 153657
Affinity DataKi: 5.70nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 40.3nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 102nMpH: 7.2Assay Description:The activity of the isolated JAK3 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Leu-Pro-Leu-Asp-Lys-Asp-Ty...More data for this Ligand-Target Pair
Affinity DataKi: 131nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair