BDBM153862 US8999981, A107

SMILES C.C[C@H]1CN(CC2CC2)CCN1C(=O)N1Cc2c(NC(=O)c3ccc(F)cc3F)n[nH]c2C1(C)C

InChI Key InChIKey=RHTMJJBRXKJYQX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153862   

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153862(US8999981, A107)
Affinity DataKi:  68.9nM ΔG°:  -9.93kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent