BDBM158478 US10189853, sunitinib::US9029401, Sunitinib::US9695181, Sunitinib

SMILES: CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3cccc(F)c23)c1C

InChI Key: InChIKey=UQQZPUPMXFCRML-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 158478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM158478 (US9029401, Sunitinib | US9695181, Sunitinib | US10...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM158478 (US9029401, Sunitinib | US9695181, Sunitinib | US10...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM158478 (US9029401, Sunitinib | US9695181, Sunitinib | US10...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM158478 (US9029401, Sunitinib | US9695181, Sunitinib | US10...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.9	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha (Human)	BDBM158478 (US9029401, Sunitinib | US9695181, Sunitinib | US10...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83.1	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Human)	BDBM158478 (US9029401, Sunitinib | US9695181, Sunitinib | US10...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM158478 (US9029401, Sunitinib | US9695181, Sunitinib | US10...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
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