BDBM158485 US10383835, Compound 2228::US9029401, 2227
SMILES: CNC(=O)c1ccc(O[C@H]2CCC(CC2)NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1
InChI Key: InChIKey=JNPWHXLRBKEIPP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 158485 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Bifunctional epoxide hydrolase 2
(Human) | BDBM158485
(US9029401, 2227 | US10383835, Compound 2228) | GoogleScholar
| UniChem
| | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Human) | BDBM158485
(US9029401, 2227 | US10383835, Compound 2228) | GoogleScholar
| UniChem
| | n/a | n/a | 340 | n/a | n/a | n/a | n/a | 7.5 | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf [V600E]
(Human) | BDBM158485
(US9029401, 2227 | US10383835, Compound 2228) | GoogleScholar
| UniChem
| | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epoxide hydrolase
(Horse) | BDBM158485
(US9029401, 2227 | US10383835, Compound 2228) | GoogleScholar
| UniChem
| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epoxide hydrolase
(Sheep) | BDBM158485
(US9029401, 2227 | US10383835, Compound 2228) | GoogleScholar
| UniChem
| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epoxide hydrolase 1
(Cat) | BDBM158485
(US9029401, 2227 | US10383835, Compound 2228) | GoogleScholar
| UniChem
| | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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