BDBM159041 US9034866, 516

SMILES Cc1nnc(o1)[C@](C)(O)C#Cc1ccc2OC[C@](C)(F)c3sc(nc3-c2c1)C(N)=O

InChI Key InChIKey=FRKNOOYNESKUDL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159041   

LigandPNGBDBM159041(US9034866, 516)
Affinity DataKi:  4.20nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
US Patent

LigandPNGBDBM159041(US9034866, 516)
Affinity DataKi:  10nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
US Patent