BDBM159784 US10966980, Example 135::US9035074, 34A

SMILES: CN([C@@H]1C[C@H](CS(=O)(=O)[C@@H]2CC[C@H](C2)C#N)C1)c1ncnc2[nH]ccc12

InChI Key: InChIKey=HRRLZKHIEGDCQZ-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 159784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	801	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	801	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	286	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM159784 (US9035074, 34A | US10966980, Example 135) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	682	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair