BDBM162366 BDBM162611::US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]amino-1-(2,2-dimethylpropanoyl)-1H-pyrazol-3-yl)-1,2-dihydropyridin-2-one

SMILES: CC(C)(C)C(=O)n1nc(cc1NCc1ccc(Cl)s1)-c1ccc[nH]c1=O

InChI Key: InChIKey=IELDEMOVCFANHT-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 162366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
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Prothrombin (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
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Prothrombin (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor VII (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor IX (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor XI (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor XII (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor V (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Chymotrypsinogen B2 (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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Plasminogen (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tryptase delta (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Plasma kallikrein (Human)	BDBM162366 (US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
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