BDBM16631 6-[(5,7-dichloro-1-benzofuran-2-)sulfonyl]-2,3-dihydropyridazin-3-one::CHEMBL239440::Heterocyclic Sulfonylpyridazinone, 19l

SMILES Clc1cc(Cl)c2oc(cc2c1)S(=O)(=O)c1ccc(=O)[nH]n1

InChI Key InChIKey=OLKIXQGJDUXXTC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16631   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16631(6-[(5,7-dichloro-1-benzofuran-2-)sulfonyl]-2,3-dih...)
Affinity DataIC50:  87nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM16631(6-[(5,7-dichloro-1-benzofuran-2-)sulfonyl]-2,3-dih...)
Affinity DataIC50:  87nMAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed