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BDBM167954 1-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3j)

SMILES: OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=ZYCGVUUIDVXHPY-UHFFFAOYSA-N

Data: 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 167954
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM167954 (1-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.98	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM167954 (1-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	307	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor 2 (Human)	BDBM167954 (1-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	145	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM167954 (1-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	78.9	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair