BDBM17015 (3Z)-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::CHEMBL86755::Indolinone based inhibitor, 1::Oxindole I

SMILES: O=C1Nc2ccccc2\C1=C\c1ccc[nH]1

InChI Key: InChIKey=SEZFNTZQMWJIAI-UHFFFAOYSA-N

Data: 15 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 17015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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SRSF protein kinase 1 (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	361	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 17B (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	353	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase tousled-like 2 (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
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3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.2	22
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Insulin-like growth factor 1 receptor (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Mouse)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage colony-stimulating factor 1 receptor [538-678,753-922] (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	22
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Macrophage colony-stimulating factor 1 receptor [538-678,753-922] (Human)	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	7.5	22
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Macrophage colony-stimulating factor 1 receptor [538-972] ()	BDBM17015 (CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.5	22
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