BDBM17151 2-imino-thiazolidin-4-one analog, 13::4-(5-{1-[(5Z)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]ethyl}furan-2-yl)benzene-1-sulfonamide

SMILES C\C(=C1\SC(=N)NC1=O)c1ccc(o1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=AKFVRSQELXTCFW-JYRVWZFOSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17151   

TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM17151(2-imino-thiazolidin-4-one analog, 13 | 4-(5-{1-[(5...)
Affinity DataIC50:  430nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM17151(2-imino-thiazolidin-4-one analog, 13 | 4-(5-{1-[(5...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair