BDBM18534 6-[bis(cyclopropylmethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::6-dialkylamino-4-trifluoromethylquinolin-2(1H)-one, 4h

SMILES FC(F)(F)c1cc(=O)[nH]c2ccc(cc12)N(CC1CC1)CC1CC1

InChI Key InChIKey=UKEIQRSJMOAAPW-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18534   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18534(6-[bis(cyclopropylmethyl)amino]-4-(trifluoromethyl...)
Affinity DataKi:  6.30nM ΔG°:  -11.6kcal/mole EC50:  1.90nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed