BDBM18755 1,2-naphthalein derivative, 1::3,3-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),7,10,12-pentaen-5-one

SMILES: Oc1ccc(cc1)C1(OC(=O)c2ccc3ccccc3c12)c1ccc(O)cc1

InChI Key: InChIKey=QXMVPKDATXGFFJ-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidylate synthase (Cryptococcus neoformans)	BDBM18755 (3,3-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Thymidylate synthase (Escherichia coli (strain K12))	BDBM18755 (3,3-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.40E+3	-7.18	n/a	n/a	n/a	n/a	n/a	7.4	20
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Thymidylate synthase (Lactobacillus casei)	BDBM18755 (3,3-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10E+4	-6.65	n/a	n/a	n/a	n/a	n/a	7.4	20
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Dihydrofolate reductase (Human)	BDBM18755 (3,3-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Thymidylate synthase (Human)	BDBM18755 (3,3-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.32E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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