BDBM18775 5-(4-chlorophenyl)-6-methylpyrimidine-2,4-diamine::CHEMBL21357::P37

SMILES: Cc1nc(N)nc(N)c1-c1ccc(Cl)cc1

InChI Key: InChIKey=SNBBQZGVKQEBQT-UHFFFAOYSA-N

Data: 6 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 18775   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18775 (CHEMBL21357 | 5-(4-chlorophenyl)-6-methylpyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-hexosaminidase subunit alpha (Human)	BDBM18775 (CHEMBL21357 | 5-(4-chlorophenyl)-6-methylpyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (malaria parasite P. vivax)	BDBM18775 (CHEMBL21357 | 5-(4-chlorophenyl)-6-methylpyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.780	-12.4	1.95E+3	n/a	n/a	n/a	n/a	7.0	25
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18775 (CHEMBL21357 | 5-(4-chlorophenyl)-6-methylpyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18775 (CHEMBL21357 | 5-(4-chlorophenyl)-6-methylpyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N] (malaria parasite P. vivax)	BDBM18775 (CHEMBL21357 | 5-(4-chlorophenyl)-6-methylpyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		63.4	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18775 (CHEMBL21357 | 5-(4-chlorophenyl)-6-methylpyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18775 (CHEMBL21357 | 5-(4-chlorophenyl)-6-methylpyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		142	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair