BDBM18780 6-ethyl-5-(4-methoxyphenyl)pyrimidine-2,4-diamine::CHEMBL281412::P18

SMILES: CCc1nc(N)nc(N)c1-c1ccc(OC)cc1

InChI Key: InChIKey=SRYOSRABCMAHOE-UHFFFAOYSA-N

Data: 6 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 18780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18780 (CHEMBL281412 | 6-ethyl-5-(4-methoxyphenyl)pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-hexosaminidase subunit alpha (Human)	BDBM18780 (CHEMBL281412 | 6-ethyl-5-(4-methoxyphenyl)pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18780 (CHEMBL281412 | 6-ethyl-5-(4-methoxyphenyl)pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (malaria parasite P. vivax)	BDBM18780 (CHEMBL281412 | 6-ethyl-5-(4-methoxyphenyl)pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.01	-12.3	350	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18780 (CHEMBL281412 | 6-ethyl-5-(4-methoxyphenyl)pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N] (malaria parasite P. vivax)	BDBM18780 (CHEMBL281412 | 6-ethyl-5-(4-methoxyphenyl)pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		37.8	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18780 (CHEMBL281412 | 6-ethyl-5-(4-methoxyphenyl)pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18780 (CHEMBL281412 | 6-ethyl-5-(4-methoxyphenyl)pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair