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BDBM188500 3,4,7,7-Tetramethyl-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one (3)::US10137122, Compound 42

SMILES: CC1c2c(C)[nH]nc2NC2=C1C(=O)CC(C)(C)C2

InChI Key: InChIKey=BIYAZNGCRGXNLF-UHFFFAOYSA-N

Data: 4 IC50 1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 188500
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 alpha (Human)	BDBM188500 (3,4,7,7-Tetramethyl-2,4,6,7,8,9-hexahydro-5H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM188500 (3,4,7,7-Tetramethyl-2,4,6,7,8,9-hexahydro-5H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM188500 (3,4,7,7-Tetramethyl-2,4,6,7,8,9-hexahydro-5H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM188500 (3,4,7,7-Tetramethyl-2,4,6,7,8,9-hexahydro-5H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	401	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM188500 (3,4,7,7-Tetramethyl-2,4,6,7,8,9-hexahydro-5H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	537	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair