BDBM1892 1-[2-(2-ethoxy-6-fluorophenyl)ethyl]-3-(5-methylpyridin-2-yl)thiourea::N-(2-(2-Ethoxy-6-fluorophenylethyl)-N -(2-(5-methylpyridyl))thiourea::PETT Analog 59

SMILES CCOc1cccc(F)c1CCNC(=S)Nc1ccc(C)cn1

InChI Key InChIKey=QOWQLJPKVFLTTM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1892   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1892(1-[2-(2-ethoxy-6-fluorophenyl)ethyl]-3-(5-methylpy...)
Affinity DataIC50:  4.5nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed