BDBM191203 US9181266, 72

SMILES COc1ccccc1C(=O)C1CCN(CC(=O)N(CC(F)F)Cc2nc3CCOCc3c(=O)[nH]2)CC1

InChI Key InChIKey=UYBOMUVIPAWXHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191203   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Novartis

US Patent
LigandPNGBDBM191203(US9181266, 72)
Affinity DataIC50: 85nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Novartis

US Patent
LigandPNGBDBM191203(US9181266, 72)
Affinity DataIC50: 420nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent