BDBM191620 US20240317756, Compound 16::US9181263, 16::US9278100, 16

SMILES: CC#CC(=O)N1CCC[C@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12

InChI Key: InChIKey=MCHPKOULFPNIOZ-UHFFFAOYSA-N

Data: 15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 191620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM191620 (US9181263, 16 | US9278100, 16 | US20240317756, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair