BDBM191641 US9186318, 13

SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCCCC(=O)NO

InChI Key InChIKey=CDTJUAMUMLOLCG-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 191641   

TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50:  2.74E+3nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50:  6.13E+3nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50:  1.63E+3nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50:  1.19E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Beijing Konruns Pharmaceutical

US Patent
LigandPNGBDBM191641(US9186318, 13)
Affinity DataIC50:  8.30nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
In DepthDetails US Patent