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BDBM193117 US10526329, Compound 192::US11072611, Compound 192::US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)piperazin-1-yl)-2-ethylimidazo[1,2-a]pyridin-3-yl)-4-(4-fluorophenyl)-N-methylthiazol-2-amine
SMILES: CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(F)cc1)N1CCN(Cc2cnc[nH]2)CC1
InChI Key: InChIKey=REMDJYSRAUFISE-UHFFFAOYSA-N
Data: 7 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Autotaxin (Human) | BDBM193117![]() (US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)p...) | GoogleScholar | UniChem | n/a | n/a | 750 | n/a | n/a | n/a | n/a | 8.5 | 25 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Autotaxin (Human) | BDBM193117![]() (US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)p...) | GoogleScholar | UniChem | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Autotaxin (Human) | BDBM193117![]() (US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)p...) | GoogleScholar | UniChem | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Autotaxin (Human) | BDBM193117![]() (US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)p...) | GoogleScholar | UniChem | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Autotaxin (Human) | BDBM193117![]() (US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)p...) | GoogleScholar | UniChem | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Autotaxin (Rat) | BDBM193117![]() (US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)p...) | GoogleScholar | UniChem | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Autotaxin (Human) | BDBM193117![]() (US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)p...) | GoogleScholar | UniChem | n/a | n/a | 771 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||