BDBM19592 (2S)-N-[2-(5-fluoro-2,3-dihydro-1H-indol-1-yl)ethyl]-4-methyl-2-[(3-methylphenyl)formamido]pentanamide::arylaminoethyl amide, 3h

SMILES CC(C)C[C@H](NC(=O)c1cccc(C)c1)C(=O)NCCN1CCc2cc(F)ccc12

InChI Key InChIKey=QZBJWYBUXVGFSV-NRFANRHFSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19592   

TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19592((2S)-N-[2-(5-fluoro-2,3-dihydro-1H-indol-1-yl)ethy...)
Affinity DataKi:  11nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19592((2S)-N-[2-(5-fluoro-2,3-dihydro-1H-indol-1-yl)ethy...)
Affinity DataKi:  80nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19592((2S)-N-[2-(5-fluoro-2,3-dihydro-1H-indol-1-yl)ethy...)
Affinity DataKi:  98nM ΔG°:  -9.94kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed