BDBM19715 (2S)-3-cyclohexyl-2-(morpholin-4-ylcarbonylamino)-N-[(2S)-1-{[4-(trifluoromethoxy)phenyl]amino}butan-2-yl]propanamide::arylaminoethyl amide deriv. 29

SMILES CC[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)N1CCOCC1

InChI Key InChIKey=BQJFNSUGTXLHFL-UGKGYDQZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19715   

TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19715((2S)-3-cyclohexyl-2-(morpholin-4-ylcarbonylamino)-...)
Affinity DataKi:  6nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19715((2S)-3-cyclohexyl-2-(morpholin-4-ylcarbonylamino)-...)
Affinity DataKi:  11nM ΔG°:  -11.3kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19715((2S)-3-cyclohexyl-2-(morpholin-4-ylcarbonylamino)-...)
Affinity DataKi:  130nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed