BDBM198124 Panobinostat

SMILES Cc1[nH]c2ccccc2c1CCNCc1ccc(C=CC(=O)NO)cc1

InChI Key InChIKey=FPOHNWQLNRZRFC-ZHACJKMWSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198124   

TargetHistone deacetylase 6 [440-798](Danio rerio)
University Of Pennsylvania

LigandPNGBDBM198124(Panobinostat)
Affinity DataKi:  1.40nM ΔG°:  -12.1kcal/mole IC50:  2.5nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed