BDBM198858 US9221797, 21

SMILES COCCN(C)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key InChIKey=JLYXGCSWHPWBKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198858   

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM198858(US9221797, 21)
Affinity DataIC50:  1.70nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor [555-568](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM198858(US9221797, 21)
Affinity DataIC50:  2.60nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent