BDBM20620 2-(3-hydroxyphenyl)-1-{4-[4-(2-methylpropyl)piperazin-1-yl]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol::Piperazine Derivative, 47

SMILES CC(C)CN1CCN(CC1)c1ccc(cc1)C1N(CCc2cc(O)ccc12)c1cccc(O)c1

InChI Key InChIKey=KOYKOWFMIFLPJS-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20620   

TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20620(2-(3-hydroxyphenyl)-1-{4-[4-(2-methylpropyl)pipera...)
Affinity DataIC50:  1.95E+3nM EC50:  491nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20620(2-(3-hydroxyphenyl)-1-{4-[4-(2-methylpropyl)pipera...)
Affinity DataIC50:  119nM EC50:  31.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed