BDBM20648 4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-N,5-dimethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide::pyrrolo[2,1-f][1,2,4]triazine analogue, 11a

SMILES CNC(=O)c1cn2ncnc(Nc3cc(ccc3C)C(=O)NOC)c2c1C

InChI Key InChIKey=GLQHXGSWFVZXAN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20648   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20648(4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-N,5...)
Affinity DataIC50:  23nM EC50:  580nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed