BDBM20674 ethyl N-(4-methyl-3-{[5-methyl-6-(propan-2-ylcarbamoyl)pyrrolo[1,2-a][1,2,4]triazin-4-yl]amino}phenyl)carbamate::pyrrolo[2,1-f][1,2,4]triazine analogue, 21h

SMILES CCOC(=O)Nc1ccc(C)c(Nc2ncnn3cc(C(=O)NC(C)C)c(C)c23)c1

InChI Key InChIKey=FDKNVSUYRDPGNB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20674   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20674(ethyl N-(4-methyl-3-{[5-methyl-6-(propan-2-ylcarba...)
Affinity DataIC50:  7.70nM EC50:  110nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed