BDBM20776 8-[(7-chloro-1,3-benzothiazol-2-yl)sulfanyl]-9-[2-(morpholin-4-yl)ethyl]-9H-purin-6-amine::Benzothiazole analogue, 34

SMILES Nc1ncnc2n(CCN3CCOCC3)c(Sc3nc4cccc(Cl)c4s3)nc12

InChI Key InChIKey=DKJQJJXMNYJZFE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20776   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Conforma Therapeutics

LigandPNGBDBM20776(8-[(7-chloro-1,3-benzothiazol-2-yl)sulfanyl]-9-[2-...)
Affinity DataEC50:  250nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed